B3 is involved in enzyme reactions, metabolism, and energy production. It is given in pharmacologic doses to lower LDL-cholesterol and triglycerides and raise HDL-cholesterol. B3 is found in lean meats, eggs, fish, whole grain cereals and legumes. Severe deficiency in conjunction with a low-protein diet causes: Pellagra - classic symptoms are dermatitis, diarrhea, and dementia; may also cause a rash in areas exposed to the sun. Deficiencies also seen with alcoholism, cirrhosis, Hartnup disease, Crohn's disease, and carcinoid syndrome. Niacin synthesis requires adequate B6, B2, iron, and copper. Up to 60% of niacin is synthesized from tryptophan. Report Includes: Nicotinamide and Nicotinic Acid Alternative Names: Nicotinic acid, Nicotinamide, Vitamin P, Vitamin PP