The GI Pathogen Profile, uses multiplex PCR system, tests for 14 Viruses, parasites, and bacteria, and offers new opportunities for the rapid, accurate diagnosis and prompt treatment of diarrheal illnesses which can improve patient outcomes and clinical success. While bacteria and parasites are the primary cause of food & water-borne diarrheal illness (48 million infections/year), the vast majority of acute diarrheal illness is caused not by bacteria or parasites, but by viral infections. In fact, Norovirus is the primary gastrointestinal infection occurring in the United States. Even though testing for pathogenic bacteria and parasite is commonly available, there has been limited availability of viral testing until recently. Acute gastroenteritis may contribute to patient morbidity and even mortality, if the illness progresses to severe dehydration. Also, the identification of reportable diseases is imperative to prevent large outbreaks, especially for highly contagious or food-borne illnesses, and many gastrointestinal illnesses have very similar clinical presentations. Most GI Pathogen Profile results can be provided within one business day of sample receipt with 99.9% overall negative predictive value. As a result, you can begin targeted treatment immediately, for greater therapeutic efficacy and reduced risk of complications & side effects associated with incorrect treatment or unwarranted antimicrobial administration. Rapid diagnosis allows for better treatment decisions, as antimicrobial agents have no effect on viral illness, and the indiscriminate use of antibiotics may increase bacterial resistance. Certain pathogenic bacterial and parasitic infections may require antimicrobial treatment, while other infections warrant rehydration and supportive therapies. Knowing the difference allows the treating physician to practice good antimicrobial stewardship. This test is useful for: Chronic or acute diarrhea Bloody stool Travelers diarrhea Abdominal pain Fever & vomiting Immuno-compromised patients Geriatric patients Chronic disease patients (heart disease, aortic grafts, diabetes, chronic renal disease) Observed cluster or suspected outbreak of diarrheal illness Analytes tested: Adenovirus F40&41 Campylobacter (C. jejuni, C. coli and C. lari) Clostridium difficile (Toxin A&B) Cryptosporidium (C. parvum and C. hominis) Entamoeba histolytica Enteroaggregative E. coli (EAEC) Enterotoxigenic E. coli (ETEC) lt & st Escherichia coli O157 Giardia duodenalis (AKA intestinalis & lamblia) Norovirus GI&GII Rotavirus A Salmonella spp. Shiga-like toxin-producing E. coli (STEC) stx1&stx2 Vibrio cholerae Additional Biomarkers Available for add-on at additional cost: Bacteriology, aerobic Microbiology Profile