also known as Cholesterol in LDL/Apolipoprotein B in Serum or Plasma
Apolipoprotein B (ApoB) is a major component of the very-low-density lipoprotein (VLDL), the intermediate-density lipoprotein (IDL), and the low-density lipoprotein (LDL). ApoB plays a central role in carrying cholesterol and triglycerides from the liver and gut to utilization and storage sites. Elevated levels indicate an increased risk of cardiovascular disease, familial combined hyperlipidemia, diabetes, hypothyroidism, kidney disease, and the use of certain drugs, such as diuretics, androgens, or beta blockers. Low ApoB levels may indicate hyperthyroidism, malnutrition, Reye syndrome (a rare degenerative brain condition), cirrhosis(scarring) of the liver, and apolipoprotein B deficiency (Bassen-Kornzweig syndrome).