The Intestinal Permeability Assessment is an effective and non-invasive assessment of small intestinal absorption and barrier function in the bowel. This test analyzes urine for the clearance of two non-metabolized sugars, lactulose and mannitol, identifying intestinal permeability (“leaky gut”) and poor absorption. Both poor absorption and increased leaky gut are associated with chronic gastrointestinal imbalances, as well as many general disorders. The Intestinal Permeability Assessment gastrointestinal test directly measures the ability of two non-metabolized sugar molecules to permeate the intestinal mucosa. The patient drinks a premeasured amount of lactulose and mannitol. The degree of intestinal permeability or malabsorption is reflected in the levels of the two sugars recovered in a urine sample collected over the next 6 hours. Analytes Tested: Creatinine Lactulose Mannitol