Coupon Codes not valid for this testing. Fasting Required: No Lab: Quest Diagnostics Specimen: Blood Results: Average processing time 4-7 days Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance. Special Instructions: Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation. Includes: Estrone; Estradiol, Ultra-sensitive; Estriol Please note: Norethindrone acetate/Norethisterone acetate is known to interfere with the measurement of estrone using the Quest Diagnostics LC-MS/MS method. This test should not be used to quantitate estrone in patients taking this drug. Description: Estrogens are 18-carbon steroids secreted by the gonads, adrenal glands, and placenta. The principle estrogens are estradiol (E2), estrone (E1), and estriol (E3). E2 is the major estrogen produced by the ovaries. E1 is derived from peripheral conversion from gonadal and adrenal androstenedione. E3 is the major placental estrogen. The major circulating estrogens in non-pregnant women are E2 and E1.